Unlike many other cancers, you can often see a skin cancer which makes it easier to catch early on. Most skin cancers can be successfully treated if they’re caught early.
Treatment depends on the type, size, location and number of skin cancers you have, and whether the cancer has spread to other parts of your body.
Treatments for superficial (surface) skin cancers
Surgery
Most skin cancers are treated by surgery (cutting out the cancer). This is done using a local anaesthetic to numb your skin. Types of surgery include excision biopsy and Mohs surgery.
- Excision biopsy: This is where the lesion is completely cut out along with some of the normal surrounding tissue. The tissue is sent to the lab and if it’s confirmed to be skin cancer you may need further surgery to remove more of the surrounding skin.
- Mohs surgery: This is a more intensive type of surgery that can be used to remove large or deep cancers or cancers that come back after they’ve been treated. It can also be used for cancers that are difficult to treat by other surgical methods, such as cancers near your eye. Its especially useful for tumours with indistinct margins (where the edge isn't obvious).
If your skin cancer is small and limited to the surface of your skin, removing it through a skin biopsy may be the only treatment you need.
Cryotherapy
This is the use of extreme cold (eg, liquid nitrogen) to treat pre-cancerous skin conditions such as solar keratoses and some small skin cancers. Liquid nitrogen is applied to the tumour to freeze and kill the abnormal cells. Some pain and redness may occur afterwards, and a blister may develop on the treated area. There may be a white mark or scar from the treatment.
Topical therapy
Topical therapy means applying a cream to the skin cancer. Fluorouracil cream can be applied directly to your skin once or twice a day for several weeks. The area will become red, then there will be blistering, peeling or cracking. The skin settles and heals once the treatment has finished. Fluorouracil cream is used to treat sun-damaged skin, pre-cancerous skin lesions such as actinic keratoses (also called solar keratoses), squamous cell carcinoma in situ and for the treatment of superficial basal cell carcinoma in low risk locations.
Imiquimod cream can be used to treat pre-cancerous lesions and superficial basal cell carcinomas (BCCs). It stimulates your immune system to recognise and destroy cancer cells. You apply it to your skin, usually several times a week, for 4 to 6 weeks.
Photodynamic therapy
This uses a light source (such as a laser or even the sun) and a photosensitising cream. First, the skin with the cancer is lightly scraped and a cream is applied to make the cancer cells sensitive to light. Then a few hours later, the area is exposed to a light source, so the cancer cells can be destroyed. If you feel any pain, you’ll be given a local anaesthetic.
Radiotherapy
Radiotherapy is an option for hard-to-treat skin cancer, such as cancer on your eyelids or nose, or if you’re not medically fit for surgery. It uses high-energy X-rays to destroy cancer cells. Treatments usually occur for a short time daily or weekly. The area may become red and sore, and there may be changes in skin colour and/or texture in the long term. Sometimes radiotherapy is given at the place where a skin cancer's been removed to lower the risk of it returning in that location – especially if the laboratory analysis identified high risk factors.
Treatment for advanced or metastatic skin cancer
Advanced or metastatic skin cancer, where the cancer has spread to other parts of your body, can be harder to treat. Medicines used include targeted therapies that block the action of certain genes and proteins.
If you have advanced melanoma that has spread to other parts of your body (stage 3 or 4), you may need a combination of surgery, medicines and radiation therapy. Medicines used to treat advanced melanoma include targeted therapies and immunotherapy such as pembrolizumab (Keytruda).