Natalizumab

Natalizumab is given in hospital by slow injection into a vein in your arm (called intravenous infusion). It's given once every 4 weeks. The infusion usually takes about 1 hour. You’ll be monitored for side effects for an hour after the infusion has finished.

During the infusion

Natalizumab can cause a reaction while it's being given so you’ll be carefully monitored during the infusion and for at least 1 hour afterwards. This is to see if you have trouble breathing, or experience fever, chills, flushing, skin rash, itching, dizziness or headache. Tell the nurse immediately if any of these symptoms occur. 

Here are some things to know when you're taking natalizumab. Other things may be important as well, so ask your healthcare provider what you should know about.

• Increased risk of infections: Natalizumab weakens your body’s defence (immune) system, so you're more likely to pick up infections. It's important to avoid anyone who has chickenpox or shingles.
• Vaccines: Some vaccines shouldn't be taken if you are on natalizumab. Always check with your doctor or pharmacist first. It's safe for you to have the annual flu vaccine.
• Your memory or balance: if you or your whānau notice problems with your memory, vision or balance, contact your doctor.
• Other medicines: Natalizumab may interact with a few medicines and herbal supplements, so check with your doctor or pharmacist before starting natalizumab or before starting any new medicines, including those you may buy over-the-counter.

Like all medicines, natalizumab can cause side effects, although not everyone gets them. Often side effects improve as your body adjusts to the new medicine.