Metoprolol

Sounds like 'me-toe-pro-lol'

Key points about metoprolol

  • Metoprolol has many uses including preventing heart damage after a heart attack and treating heart failure, high blood pressure and irregular heartbeat.
  • Metoprolol is also called Betaloc CR®, Myloc CR® or Slow Lopresor®.
  • Find out how to take it safely and possible side effects.
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Metoprolol is used to treat many conditions including heart failure, high blood pressure (hypertension), and irregular heart beat. It may also be prescribed after a heart attack (to prevent heart damage). Metoprolol is also used to prevent migraine headaches.   

It belongs to a group of medicines called beta-blockers. Metoprolol works by slowing down your heart rate and making it easier for your heart to pump blood around your body. 

 

In Aotearoa New Zealand metoprolol comes as tablets – immediate release tablets (metoprolol tartrate) and controlled release tablets (metoprolol succinate).

  • Check with your pharmacist which form you're taking. 
  •  If your medicine looks different to what you were expecting, ask your pharmacist.
  • The dose of metoprolol will be different for different people.
  • Always take metoprolol exactly as your healthcare provider has told you. The pharmacy label on your medicine will tell you how much metoprolol to take, how often to take it, and any special instructions. 
  • If you're not sure how much to take, ask your healthcare provider.

  • Controlled release (CR) tablets (metoprolol succinate):
    • Take these tablets once a day.
    • Swallow the tablets whole, with a glass of water – you can halve them if you need to but don't crush or chew them.
  • Immediate release tablets (metoprolol tartrate):
    • Take these as you have been prescribed (usually 2 or 3 times a day).
    • Take your doses at the same times each day.
  • Food: You can take metoprolol with or without food.
  • Missed dose: If you forget your dose, take it as soon as you remember that day. But if it's nearly time for your next dose, just take the next dose at the usual time. Don't take double the dose.

Here are some things to know when you're taking metoprolol. Other things may be important as well, so ask your healthcare provider what you should know about.

  • Alcohol: Avoid alcohol while you're taking metoprolol, especially when you first start treatment. Alcohol can increase your risk of side effects such as feeling dizzy.
  • Driving: Metoprolol can make you feel tired and dizzy. Be careful when driving or using tools until you know how this medicine affects you.
  • Other medicines: Metoprolol interacts with some medicines, herbal supplements and rongoā Māori, so check with your healthcare provider before starting metoprolol and before starting any new products.
  • If you’re taking metoprolol for heart failure, check with your pharmacist before taking any over-the-counter anti-inflammatories such as diclofenac (eg, Voltaren Rapid) or ibuprofen (eg, Nurofen). These can also be found in cold and flu medicines and may reduce the effectiveness of metoprolol.
  • Pregnancy or breastfeeding: Talk to your healthcare provider if you're pregnant, planning a pregnancy or want to breastfeed.
  • Keep taking metoprolol regularly: Treatment with metoprolol is usually long-term. You should continue to take it unless you are advised by your doctor to stop. 
  • Don't stop taking metoprolol suddenly: This can be dangerous and make you feel unwell. Talk to your healthcare provider before stopping.

 

If you have diabetes

  • If you have diabetes, metoprolol may cause changes in your blood glucose level. This effect usually settles with time.
  • Beta-blockers may reduce the warning signs of a low blood glucose level (hypoglycaemia – often called a hypo). For example, you may not have the feeling of fast, irregular or strong heartbeats (palpitations) or tremor, which can occur when your blood glucose is going too low.
  • If you're worried about this, talk to your healthcare provider. Don't stop taking your beta-blocker without checking with your healthcare provider first. Read more about hypoglycaemia.


If you have asthma

  • If you have asthma, taking metoprolol may trigger your asthma symptoms or make them worse. Not everybody with asthma is sensitive to these medicines.
  • If you're worried about this, talk to your healthcare provider. They may be able to prescribe a different medicine or increase the dose of your asthma medicine. Read more about medicines that may trigger asthma symptoms.

Like all medicines, metoprolol can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.

Side effects What should I do?
  • Tiredness
  • Headache
  • Nausea (feeling sick) or vomiting (being sick)
  • Sore stomach
  • These are common when you first start taking metoprolol, and usually go away with time.
  • Tell your healthcare provider if they bother you.
  • Feeling dizzy
  • Feeling faint when you stand up
  • This is common when you first start taking metoprolol.
  • Don't drink alcohol.
  • Be careful when getting up from either lying down or sitting to avoid falls.
  • Cold hands and feet
  • This is common.
  • Dress warmly in cold weather, especially if you’re going to be outside for a long time.
  • Tell your healthcare provider if this bothers you.
  • Depression and low mood
  • Sexual problems
  • Tell your healthcare provider.
  • Problems with breathing, eg, chest tightness, or wheezing or swelling of the ankles or feet.
  • These are rare.
  • Tell your doctor immediately or ring Healthline 0800 611 116.
  • Signs of an allergic reaction such as skin rash, itches, swelling of the face, lips, mouth and tongue or problems breathing

  • This is rare. 
  • Stop taking metoprolol and phone 111 for  an ambulance.


Read more about medicines and side effects and reporting a reaction you think might be a side effect.

The following links have more information on metoprolol:

Metoprolol(external link) New Zealand Formulary Patient Information te reo Māori(external link)
Myloc CR(external link) Medsafe Consumer Information Sheet, NZ
Betaloc CR tablet(external link) Medsafe Consumer Information Sheet, NZ
Slow Lopressor tablet(external link) Medsafe Consumer Information Sheet, NZ


Brochures

Metoprolol Institute for Innovation and Improvement and Waitematā DHB, NZ, 2020 Black/white [PDF, 4.1 MB], colour(external link)
Metoprolol in te reo Māori(external link) My Medicines, NZ, 2023
Medicines and side effects(external link) Healthify He Puna Waiora, NZ, 2024
5 questions to ask about your medications(external link) Health Quality and Safety Commission, NZ, 2019 English(external link), te reo Māori(external link)


References

  1. Metoprolol succinate(external link) New Zealand Formulary
  2. Metoprolol tartrate(external link) New Zealand Formulary
  3. Myloc CR(external link) Medsafe datasheet, NZ 
  4. IPCA-Metoprolol tablets(external link) Medsafe datasheet, NZ 
  5. Slow-Lopresor tablets(external link) Medsafe datasheet, NZ 
  6. Beta blockers for cardiovascular conditions – one size does not fit all(external link) BPAC, NZ, 2024 
  7. Management of stable angina pectoris(external link) BPAC, NZ, 2025 
  8. A progressive approach to managing atrial fibrillation(external link) BPAC, NZ, 2024 
  9. Addressing heart failure in primary care(external link) BPAC, NZ, 2025 
  10. Hypertension in adults – the silent killer(external link) BPAC, NZ, 2023 

Brochures

metoprolol wdhb brochure

Metoprolol

Institute for Innovation and Improvement and Waitematā DHB, NZ, 2020
Colour, black/white [PDF, 4.1 MB]

metoprolol maori

Metoprolol in te reo Māori

My Medicines, NZ, 2023

Medicines and side effects
Healthify He Puna Waiora, NZ, 2024

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Credits: Healthify editorial team. Healthify is brought to you by Health Navigator Charitable Trust.

Reviewed by: Stephanie Yee, Pharmacist, Auckland.

Last reviewed: