Sumatriptan tablets

Sounds like 'soo-ma-trip-tan'

Key points about sumatriptan tablets

  • Sumatriptan is used to ease the symptoms of migraines.
  • Sumatriptan tablets are also called Sumagran®.
  • Find out how to take it safely and possible side effects.
Woman sits with hand on head and severe migraine pain

Sumatriptan is used to ease the symptoms of migraines. It works by releasing a natural chemical called serotonin, which causes the blood vessels around your brain to contract (narrow). This reverses the dilating (widening) of blood vessels that's believed to be part of the headache process. 

Sumatriptan only works when a migraine attack has already begun. It won't prevent a migraine. Don't take it before your headache begins, or during the aura phase, as it may be less effective. Read more about migraine headaches.

Sumatriptan belongs to a group of medicines called triptans.

In Aotearoa New Zealand, sumatriptan is available as tablets (50 mg and 100 mg) and an injection. The information on this page is about sumatriptan tablets. The injection may be better if you're vomiting, or if you develop a sudden migraine. Read more about sumatriptan injection.  

You can buy 2 sumatriptan tablets (50 mg) over the counter in pharmacies after talking to your pharmacist. It’s also available on a prescription written by a prescriber.

  • Do you have problems with your liver or kidneys?
  • Do you have problems with high blood pressure (hypertension)?
  • Have you had a heart attack or do you get angina (chest pain)?
  • Have you had a stroke or do you get transient ischemic attacks?
  • Are you pregnant or breastfeeding?
  • Have you ever had a seizure?
  • Are you taking medicine for depression?

If so, it’s important that you tell your healthcare provider or pharmacist before you start sumatriptan. Sometimes a medicine isn’t suitable for a person with certain conditions, or it can only be used with extra care.

Always use sumatriptan tablets exactly as your healthcare provider has told you. The pharmacy label on your medicine will tell you how much to use, how often to use it and any special instructions. Here is some guidance:

  • In adults, the usual dose is 1 tablet (50 mg or 100 mg) at the start of the migraine attack. It should work within 30 minutes.
  • If your migraine improves but then comes back, wait at least 2 hours before taking another tablet (50 mg or 100 mg).
  • Don't take more than 300 mg in 24 hours (6 of the 50 mg tablets or 3 of the 100 mg tablets).
  • If the first sumatriptan dose doesn't relieve your symptoms or help your migraine, don't take another sumatriptan dose for the same attack. It's unlikely to work.

Monthly limit

Don't use sumatriptan for more than 9 days per month. Using sumatriptan too frequently can cause medication-overuse headache or rebound headache. This headache is caused by overuse of painkillers to treat headache, including the use of triptans for migraine. The symptoms include a tension-type headache or migraine-like attack. 

Headaches often improve within 7 to 10 days after sumatriptan has been stopped. Symptoms may be worse before an improvement is seen. Read more about medication-overuse headache.

If you need to regularly use sumatriptan more than 2 times a week talk to your healthcare provider. There are other medicines that can be taken every day to prevent migraines. Read more about medicines to prevent migraines.


How to take sumatriptan tablets

  • Timing: It's best to take sumatriptan as soon as you notice headache symptoms, but you can take it after a migraine has already begun. Sumatriptan tablets usually start to work within 30 minutes after taking the tablet but may take up to 4 hours.
  • Food: Sumatriptan can be taken with or without food.
  • Swallow the tablet whole with a glass of water: Don't crush or chew sumatriptan tablets.

Here are some things to know when you're taking sumatriptan tablets. Other things may be important as well, so ask your healthcare provider what you should know about.

  • Other medicines: Sumatriptan interacts with some medicines, herbal supplements and rongoā Māori, so check with your healthcare provider or pharmacist before starting sumatriptan and before starting any new products.
  • Driving: Sumatriptan and/or migraines can make you feel tired or dizzy. Be careful when driving or using tools until you know how this medicine affects you. Limit or avoid drinking alcohol while taking sumatriptan as alcohol may increase these side-effects.
  • Pregnancy or breastfeeding: Talk to your healthcare provider if you're pregnant, planning a pregnancy or want to breastfeed.
  • Don't give sumatriptan to anyone else even if they also have migraines.

Like all medicines, sumatriptan can cause side effects, although not everyone gets them. If you're concerned about any symptoms you think might be related to your medicine, talk to your healthcare provider. The following information offers some guidance but doesn't include all possible side effects.


Common side effects

Tell your healthcare provider if these side effects bother you.

  • Feeling sleepy, tired or dizzy: Be careful when driving or using tools until you know how this medicine affects you. Don’t drink alcohol.
  • Nausea (feeling sick) or vomiting (being sick): This may be due to the migraine attack. Avoid eating until this feeling passes.


Tell your healthcare provider immediately or phone Healthline free on 0800 611 116 if these occur

  • Intense or ongoing pain, or tightness in your chest, jaw or throat.
  • Signs of serotonin syndrome(external link): Feeling agitated and restless, heavy sweating, shivering, fast heart rate or irregular heartbeat, headache, diarrhoea (runny poo) and rigid or twitching muscles. You’re at increased risk of serotonin syndrome if you recently started taking sumatriptan, recently increased the dose or are taking other medicines that can also cause serotonin syndrome.

     

Phone 111 for an ambulance or go to your nearest accident and emergency (A&E) clinic if these occur

  • Signs of an allergic reaction such as itchy skin, and rash, swollen lips or tongue, problems breathing, like a tight chest or shortness of breath.

Read more about medicines and side effects and reporting a reaction you think might be a side effect.

The following links have more information on sumatriptan:

Sumatriptan(external link) New Zealand Formulary Patient Information
Sumagran®(external link) Medsafe Consumer Medicine Information, NZ
Sumagran Active®(external link) Medsafe Consumer Medicine Information, NZ 

Brochures

Medicines and side effects(external link) Healthify He Puna Waiora, NZ, 2024
5 questions to ask about your medications (external link)Health Quality and Safety Commission, NZ, 2019 English(external link), te reo Māori(external link)

References

  1. Treatment of acute migraine(external link) New Zealand Formulary
  2. Sumatriptan(external link) New Zealand Formulary 
  3. Diagnosing and managing headache in adults in primary care(external link) BPAC, NZ, 2017 

Brochures

Medicines and side effects
Healthify He Puna Waiora, NZ, 2024

5 questions to ask about your medications

5 questions to ask about your medications

Health Quality and Safety Commission, NZ, 2019 English, te reo Māori

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Credits: Healthify editorial team. Healthify is brought to you by Health Navigator Charitable Trust.

Reviewed by: Stephanie Yee, Pharmacist, Auckland.

Last reviewed: