Ciclosporin

In Aotearoa New Zealand ciclosporin is available as an injection, capsules and a liquid solution. The information on this page is mainly about ciclosporin capsules.

• Ciclosporin capsules come in different strengths 25mg, 50mg and 100mg. 
• The dose you have will depend on:
  • how much you weigh
  • what condition is being treated
  • how well the medicine works for you
  • whether you have any side effects from this medicine.
• Your dose may be changed from time to time.
• Always take ciclosporin exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much to take, how often to take it and any special instructions.
• Read what to do if you think a child or someone else has taken a medicine that's not for them.

• Timing: Take your dose twice a day. It's best to take the doses 12 hours apart, eg, 8am and 8pm. Take your dose at about the same time each day.
• You can take ciclosporin with or without food. Avoid having large amounts of grapefruit or grapefruit juice as it can change the levels of ciclosporin in your body.
• Swallow your capsules whole with a full glass of water: Don't open or chew them.
• Avoid or limit alcohol: Avoid heavy or binge drinking because it can increase your risk of side effects, such as problems with your liver. 
• Missed dose: If you forget to take your dose, take it as soon as you remember. But if it is nearly time for your next dose, take the next dose at the right time. Don't take extra doses to make up for a forgotten dose. If you're not sure what to do, ask your healthcare provider.
• Keep taking ciclosporin regularly: Ciclosporin doesn't work straight away. It usually takes a few weeks before you notice the full benefits. If you stop ciclosporin treatment for more than a few weeks there's a risk your condition may worsen.

Here are some things to know when you're taking ciclosporin. Other things may be important as well, so ask your healthcare provider what you should know about.

Protect yourself from too much sunlight

Ciclosporin can make you more sensitive to the sun and your skin is more likely to burn.

• Avoid direct sun exposure. When outside, protect your skin by using an oil-free sunscreen.
• Apply the sunscreen to all areas especially your face, neck and ears. Read more about using sunscreen.
• Wear clothing that protects you from the sun. Wear sunglasses and a hat when outdoors.

Taking other medicines and supplements

Ciclosporin can interact with some medicines, herbal supplements and rongoā Māori, so check with your doctor or pharmacist before starting ciclosporin and before starting any new products.

You may need regular blood tests

While you're taking ciclosporin you'll need to have regular blood tests to check the treatment is working and to monitor for side effects. 

Get the flu vaccine every year

Keep your flu vaccination up to date to reduce your risk of getting the flu. It's safe for you to have the annual flu vaccine. Some vaccines should not be taken if you are taking ciclosporin. Always check with your healthcare provider first.

Tell your healthcare providers

Make sure you tell anyone providing you with health, dental or medical care that you are taking ciclosporin.

Pregnancy and breastfeeding

It's not advisable to get pregnant while taking ciclosporin. If you plan to become pregnant, or find you are pregnant, talk to your doctor. Tell your doctor if you are breastfeeding.

Like all medicines, ciclosporin can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.

Read more about medicines and side effects and reporting a reaction that you think might be a side effect.