Cholesterol lowering medicines

Key points about cholesterol lowering medicines

  • Cholesterol-lowering medicines reduce the risk of heart attack or stroke for people with high cholesterol.
  • To get the most benefit it’s important to keep taking these medicines regularly to lower your chance of heart problems.
  • Statins are the preferred cholesterol lowering medicines.
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Cholesterol-lowering medicines reduce the risk of heart attack or stroke for people with high cholesterol.

Having high cholesterol can narrow your blood vessels because fat builds up and blocks the blood vessels (atherosclerosis). Cholesterol is measured in mmol/L. Having a total cholesterol above 4 mmol/L increases your chance of having atherosclerosis.

When fatty deposits build up in the blood vessels around your heart, it’s called coronary artery disease. Having high cholesterol increases your chance of having a heart attack, a stroke or coronary artery disease.

If you have high cholesterol, even lowering it by 1 mmol/L will lower your risk of a fatal heart attack or stroke by 20%.

Although you won’t feel any different when you take these medicines, it's important to keep taking them regularly to lower your chance of heart problems.

For best results, you’re encouraged to take these medicines and have a healthy lifestyle which includes reducing alcohol intake, stopping smoking, lowering the amount of salt in your food and being more active.

There are different types of cholesterol lowering medicines, such as:

More information about each of these can be found in the sections below. 

Statins are a group of medicines used to lower cholesterol in your blood. Statins are the preferred cholesterol lowering medicines. Atorvastatin is the most commonly used medicine to lower cholesterol in Aotearoa New Zealand.

Statins slow down the cholesterol produced by your liver. The longer you take a statin, the more you reduce your risk of a heart attack, stroke or coronary artery disease. 

In Aotearoa New Zealand, the following statins are available:

Read more about statins.

Ezetimibe is a cholesterol lowering medicine often taken with statins. It works by reducing the amount of cholesterol you absorb from food. 

In Aotearoa New Zealand, ezetimibe is available as 10 mg tablets or in combination with simvastatin in the same tablet.

Read more about ezetimibe.

Bezafibrate is used to lower cholesterol (mainly triglyceride) levels in your blood. Bezafibrate is usually used in combination with a statin for people with high triglyceride levels or it's prescribed when statins can't be used to lower cholesterol.

In Aotearoa New Zealand bezafibrate is available as 200 mg or 400 mg modified-release tablets.

Read more about bezafibrate.

Acipimox is a cholesterol lowering medicine used when statins and bezafibrate haven't worked for you.

In Aotearoa New Zealand acipimox is available as 250 mg capsules.

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Credits: Healthify editorial team. Healthify is brought to you by Health Navigator Charitable Trust.

Reviewed by: Angela Lambie, Pharmacist, Auckland.

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