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Seebri Breezhaler

Also called glycopyrronium

Key points about Seebri

Seebri® contains glycopyrronium powder in a capsule form, which is for inhalation using the Breezhaler® device only.
It's a bronchodilator medicine which works by opening your airway.
Find out how to use the Seebri Breezhaler® and possible side effects.

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Seebri® is used to improve breathing problems caused by COPD, eg, wheezing, coughing and shortness of breath.

It's a long-acting bronchodilator, which means that it works throughout the day.
It works by opening air passages in your lungs making breathing easier.
Seebri should be used every day to reduce your symptoms over the long term.
Seebri contains glycopyrronium powder in a capsule form, which is for inhalation.
Do not swallow the capsules. The powder from the capsule is breathed into your lungs using the Breezhaler® inhaler.
Using an inhaler device enables the medicine to go straight into your airways when you breathe in. This means that your airways and lungs are treated, but very little of the medicine gets into the rest of your body.

In Aotearoa New Zealand Seebri comes as 50 microgram capsules for inhalation.

Seebri doesn't give immediate relief from wheezing, tight chest and shortness of breath

If you need quick relief from these symptoms, use your ‘reliever’ medicine, eg, salbutamol or terbutaline.

The dose of Seebri is 1 capsule inhaled once a day.
Do,'t swallow the capsules.
Inhale the powder in the capsule using the Breezhaler device.
Follow your doctor's instructions carefully. The pharmacy label on your medicine will tell you how much to use, how often to use it and any special instructions.

Here are some things to know when you're using Seebri. Other things may be important as well, so ask your healthcare provider what you should know about.

Keep using your Seebri Breezhaler every day. Don't stop using it, even if you feel better. Since COPD is a long-term condition, prevention with Seebri is ongoing and it will need to be used every day.
Try to use your inhaler at the same time each day, to help you to remember to use it regularly.
Driving: Be careful when driving or using tools until you know how this medicine affects you.
Missed dose: If you miss a dose, you can take it as soon as you remember. But if it's nearly time for your next dose, just take your next dose at the right time.

To get the most benefit, it’s important to use the correct technique. Ask your healthcare provider to show you how to use a Breezhaler device.

The video below provides some guidance on how to use a Breezhaler device. The Breezhaler is the name of the device used to deliver the medicine to your lungs and airways. There are different names for each Breezhaler depending on the medicines inside the device.

Your Breezhaler may be a different colour to the one in the video below. It's important to know the name and colour of your Breezhaler, eg, Seebri®, Onbrez® or Ultibro®. Read more about understanding your medicines.

Video: How to use your Breezhaler device

(Healthify He Puna Waiora & Auckland District Health Board, NZ, 2018)

Using a Breezhaler device

Open: Remove the cover to expose the mouthpiece. Pull back the mouthpiece to reveal the capsule chamber.
Insert the capsule: The capsules come packaged in a foil wrapping. Pull back the foil edges to release 1 capsule. Don't remove the capsule by pushing it through the foil – this will damage the capsule. Place the capsule into the capsule chamber. Close the mouthpiece until you hear a click.
Pierce the capsule: Hold the inhaler upright and press both side buttons at the same time. You should hear a click as the capsule is pierced. Then release the side buttons.
Inhale your dose: Put the mouthpiece into your mouth and seal your lips firmly around it. Breathe in rapidly and deeply until your lungs are full and hold your breath for 10 seconds. You will hear the sound of the capsule vibrating in the chamber.
Take 2 breaths from 1 capsule: To get your full daily dose, you must use your inhaler twice from the same capsule.
Discard the used capsule: After inhaling your dose, open the mouthpiece and throw away the used capsule. Close the mouthpiece and the lid of the inhaler.

Cleaning and storing a Breezhaler: You can clean the device by wiping the mouthpiece with a clean dry tissue. Don't wash the mouthpiece or allow it to get wet when you're cleaning it. You will get a new Breezhaler with your repeat prescription every month. Close the device when it's not in use. Store it in a cool dry place, away from heat and moisture.

Like all medicines Seebri can cause side effects, although not everyone gets them. Often side effects improve as your body adjusts to the new medicine.

Side effects	What should I do?
Dry mouth A change in voice (hoarse voice) A different taste in your mouth Diarrhoea (runny poos) Sore stomach Headache Muscle aches and pains Problems sleeping	These are common. After using your inhaler device, rinse your mouth to prevent dry mouth and throat irritation. Tell your doctor if these bother you.
Cough Sore throat, blocked nose Difficulty urinating (peeing)	These are not common. Tell your doctor if these bother you.
Blurred vision Dizziness	Don't drive or use machinery. Don't drink alcohol. Tell your doctor if these bother you.
Changes in your heartbeat (fast or irregular)	Tell your doctor immediately or phone Healthline on 0800 611 116.
Difficulty breathing or worsening of your breathing problem.	Tell your doctor immediately or phone Healthline on 0800 611 116.