Bezafibrate

Sounds like 'Be-za-fy-brate'

Key points about bezafibrate

  • Bezafibrate is used to lower raised cholesterol.
  • Bezafibrate is also called Bezalip or Bezalip Retard.
  • Find out how to take it safely and possible side effects. 
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Bezafibrate is used to lower cholesterol (mainly triglycerides) levels in your blood. Bezafibrate is usually used in combination with a statin in people with high triglyceride levels or it is prescribed when statins cannot be used to lower cholesterol.

In New Zealand bezafibrate is available as Bezalip® or modified-release tablets, Bezalip Retard®.

  • Your dose of bezafibrate will depend on whether you have been prescribed Bezalip® or Bezalip Retard®. 
  • The usual dose of Bezalip® is 200 milligrams three times daily, and the usual dose of Bezalip Retard® is 400 milligrams once daily.   
  • Always take your bezafibrate exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much bezafibrate to take, how often to take it, and any special instructions.

Bezalip®

Bezalip® is taken 2 or 3 times daily, with or after food. Take Bezalip at about the same times each day. To reduce your cholesterol, you must keep taking bezafibrate every day. 

Bezalip Retard®

Bezalip Retard® is taken once daily, with or after food.  Swallow your tablets whole with a glass of water – do not chew, crush, or break them. To reduce your cholesterol, you must keep taking bezafibrate every day.  

Here are some things to know when you're taking bezafibrate. Other things may be important as well, so ask your healthcare provider what you should know about.

  • Other medicines: bezafibrate interacts with some medications, herbal supplements an rongoā Māori, so check with your doctor or pharmacist before starting bezafibrate and before starting any new products.

Like all medicines, bezafibrate can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.

Side effects What should I do?
  • Stomach upset
  • Bloating or gas in the tummy
  • Nausea (feeling sick) or dizziness
  • These are quite common when you first start taking bezafibrate and usually go away with time
  • Take your tablets with or just after food
  • Tell your doctor if troublesome
  • Signs of problems with your liver such as yellowing of the skin or eyes, dark urine, pain in the abdomen
  • Tell your doctor immediately or ring HealthLine 0800 611 116
  • Signs of problems with your muscles such as muscle aches and pain, pain in your legs, muscle cramps, tenderness or weakness
  • These symptoms are more likely if you are using bezafibrate with a statin
  • Tell your doctor immediately or ring HealthLine 0800 611 116
Read more about medicines and side effects and reporting a reaction you think might be a side effect.

The following links provide further information on bezafibrate.
Medsafe Consumer Information Sheets:

Bezalip(external link)
Bezalip Retard(external link)

References

  1. Bezafibrate(external link) New Zealand Formulary

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Credits: Sandra Ponen, Pharmacist, Healthify He Puna Waiora. Healthify is brought to you by Health Navigator Charitable Trust.

Reviewed by: Angela Lambie, Pharmacist, Auckland

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