Paroxetine is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI)Paroxetine is used to treat a number of mental health conditions including depression, obsessive-compulsive disorder (OCD),panic attacks, anxiety or post-traumatic stress disorder (PTSD).
We don't know for certain, but researchers think that SSRIs work by increasing the activity of serotonin which is thought to improve mood, emotion and sleep. Read more about SSRIs
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Paroxetine
Sounds like 'pa-rox-e-teen'
Key points about paroxetine
- Paroxetine is used to treat a number of mental health conditions including depression, panic attacks and anxiety.
- Paroxetine is also called Loxamine® or Aropax®.
- Find out how to take it safely and possible side effects.
If you need help or want to talk to somebody about your mental health, you can get support from any of the following:
- Free call or text 1737 any time for support from a trained counsellor
- Lifeline 0800 543 354 (0800 LIFELINE) or free text 4357 (HELP)
- Suicide Crisis Helpline 0508 828 865 (0508 TAUTOKO)
- Healthline 0800 611 116
- Samaritans 0800 726 666.
Dose
Always take your paroxetine exactly as your doctor has told you. The pharmacy label on your medicine will tell you how much paroxetine to take, how often to take it, and any special instructions.
- In New Zealand paroxetine is available as tablets (20 mg)
- The dose of paroxetine will be different for different people and depends on the condition being treated.
- Your doctor will usually start you on a low dose and if needed, will increase your dose slowly. This allows your body to get used to the medicine and reduces the chance of side effects.
How to take paroxetine
- Take paroxetine once a day, in the morning, after breakfast. Take your dose at the same time each day. It is best to take paroxetine with food.
- If you forget to take your dose, take it as soon as you remember. But if it is nearly time for your next dose, just take it at the right time. Don't take double the dose.
- Keep taking paroxetine every day. It may take 4 to 6 weeks before you notice the full benefits of paroxetine and you should start to feel better after 1 to 2 weeks. Some people notice side effects in the first few weeks before they start to feel better. Paroxetine is often needed for at least a few months. Your doctor will discuss with you how long to take it for; this depends on what you are taking it for, and how well it is working.
- If you think paroxetine is not working for you. Do not stop taking it suddenly; talk to your doctor or nurse before stopping. It is usually best to stop taking paroxetine very slowly to avoid side effects.
Here are some things to know when you're taking paroxetine. Other things may be important as well, so ask your healthcare provider what you should know about.
- Limit alcohol intake while you are taking paroxetine. Alcohol can increase your chance of side effects such as drowsiness and reduced concentration.
- Avoid driving and doing other tasks where you need to be alert until you know how this medicine affects you.
- Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
- Paroxetine can interact with some medicines (including anticoagulants and anti-inflammatories such as ibuprofen), herbal supplements (such as St John's Wort), and recreational drugs, so check with your doctor or pharmacist before starting paroxetine and before starting any new products.
- If you have diabetes, you may need to check your blood glucose more often because paroxetine can affect the levels of glucose in your blood.
Like all medicines, paroxetine can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine.
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Read more about medicines and side effects and reporting a reaction you think might be a side effect. |
The following links have more information on paroxetine.
Paroxetine Patient Information(external link) NZ Formulary, NZ
Loxamine(external link) Medsafe Consumer Information Sheets, NZ
Resources
Paroxetine New Zealand Formulary, 2022
5 questions to ask about your medications(external link) Health Quality and Safety Commission, NZ, 2019 English(external link), te reo Māori(external link)
References
- Paroxetine(external link) NZ Formulary, NZ 2022
- Selective serotonin re-uptake inhibitors(external link) NZ Formulary, NZ 2022
Brochures
Paroxetine
New Zealand Formulary, 2022
Medicines and side effects
Healthify He Puna Waiora, NZ, 2024
Health Quality and Safety Commission, NZ, 2019 English, te reo Māori
Credits: Healthify He Puna Waiora Pharmacists. Healthify is brought to you by Health Navigator Charitable Trust.
Reviewed by: Sandra Ponen, Pharmacist
Last reviewed:
Page last updated: