Medicine labels – what do the special instructions mean?

Key points about medicine labels and special instructions

  • Many medicine labels have special instructions and warning statements on them.
  • These list the types of things you should or shouldn’t do while taking the medicine.
  • If your medicine has any of the following instructions, make sure you take your medicine in that way.
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Understanding medicine labels is part of using medicines safely. If you are unsure about anything, ask your pharmacist.

The following is a guide to some special instructions and warning statements that appear on medicine labels and what they mean. If your medicine has any of the following instructions, make sure you take your medicine in that way.

  • All tablets and capsules should be taken with water.
  • Some medicines can cause stomach problems, indigestion and problems with your throat and oesophagus (the pipe between your throat and stomach) if they are not swallowed properly.
  • Taking them with a large glass of water helps to wash them down.  

  • Taking some medicines at the same time as eating may prevent your body absorbing the medicine, and it may not work as well as it should.
  • This is because food, and even some drinks, can affect the way these medicines work. 
  • To take your medicines on an empty stomach, take your medicine first and eat one hour later, OR you can eat first and take the medicine 2 hours later.
  • Read more about medicines and food.

  • Taking some medicines with alcohol can cause problems.
  • In most cases, it increases the risk of side effects such as sleepiness or changes the effect the medicine has. 
  • Read more about alcohol and medicines.

  • It's dangerous to stop some medicines suddenly, especially if you have been taking them for a few weeks or months.
  • For these medicines, it's best to talk to your doctor and make a plan to reduce your dose slowly. 
  • If you think your medicine has caused a side effect, talk to your doctor. They may be able to lower your dose or change the medicine. 
  • Don't suddenly stop taking your medicine unless your doctor tells you to.

  • Eating grapefruit or drinking grapefruit juice can affect some medicines. In most cases, it increases the level of the medicine in your blood. This can increase the risk of side effects or change the effect the medicine has. 
  • Read more about grapefruit and medicines.

  • Taking some medicines at the same time as indigestion remedies (antacids), iron or calcium may prevent your body absorbing the medicine, and it may not work as well as it should.
  • The warning about calcium includes vitamins and medicines that contain calcium and calcium-containing food such as milk and cheese.

  • Taking some medicines with alcohol can cause problems. In most cases, it can increase the risk of side effects such as sleepiness or change the effect the medicine has.
  • You should NOT stop taking the medicine if you need to drive or operate machinery. Instead you should take special care until you know how the medicine affects you, or arrange not to drive or operate machinery while you are taking the medicine.
  • The term ‘limit’ means that you should only have a moderate amount of alcohol. This is to avoid you stopping your medicines because you choose to drink alcohol, even though it's best not to drink alcohol with these medicines.
  • There are some medicines that have bad side effects and make you feel very unwell if they are taken with alcohol. Your pharmacist will talk to you about this. 
  • Read more about alcohol and medicines.

  • Some medicines may make your skin more sensitive if you are in the sun and increase your risk of sunburn. This is due to a chemical reaction in your skin from the medicine. 
  • Read more about medicines and sun exposure.

  • Every medicine should be stored as recommended because storage information is based on stability tests done at certain temperatures for certain periods of time. 
  • For medicines that need to be kept in the fridge, store them between 2º and 8ºC. 
  • These medicines should not be frozen because freezing may affect the medicine.

  • Some medicines are given a short expiry date because they are less stable or there is risk if they are used for a longer time.
  • It's best not to use a medicine that has expired. The shelf life or expiry date of a medicine is the length of time that tests have shown it stays effective and safe if properly stored. 
  • Read more about medicines and expiry dates.

Resources

Taking your medicine safely(external link)(external link) Health Quality and Safety Commission NZ, 2012
5 questions to ask about your medications(external link) Health Quality and Safety Commission, NZ, 2019 English(external link), te reo Māori(external link)

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Credits: Sandra Ponen, Pharmacist, Healthify He Puna Waiora. Healthify is brought to you by Health Navigator Charitable Trust.

Reviewed by: Angela Lambie, Pharmacist, Auckland

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