Here are some things to know when you're taking Jardiamet. Other things may be important as well, so ask your healthcare provider what you should know about.
You are at increased risk of fungal genital infections (thrush)
Jardiamet causes you to pee more and have more glucose in your urine, which increases your risk of getting thrush around the vagina or penis. Germs (bacteria and fungus) like to grow in body fluids with a high sugar content. As your blood glucose level decreases, this tends to settle.
Washing your genital area with warm water using non-perfumed soap and avoiding wearing tight underwear will reduce your risk. Also any drops of pee left behind on the penis or vagina need to be removed.
- People with a vagina, should wash their vulval area twice a day. After peeing, rinse the area with water and then pat dry. If rinsing is not possible, pat dry carefully with toilet paper.
- People with a penis should wash their groin area at least once a day. After peeing, rinse your penis with water and then pat dry. If rinsing is not possible, pat dry carefully with toilet paper. Uncircumcised people need to fully retract the foreskin before they pee, to avoid drops of urine spilling into the foreskin fold.
If you get any irritation or itching in your genital area, contact your healthcare provider immediately. Thrush is easily treated with an anti-fungal cream.
Have a sick day plan
If you are unwell, stop taking Jardiamet. Taking Jardiamet when you are unwell increases your risk of high ketones levels, which can cause a serious but rare side effect called diabetic ketoacidosis (DKA). Only restart your Jardiamet when you are well AND eating and drinking normally.
If you have nausea (feeling sick), vomiting (being sick) or tummy pain, you need to have a finger prick blood test immediately to check your ketone levels. This can be done at your GP clinic, after hours medical centre or hospital.
Talk to your healthcare team before making any big changes to your diet
If you start eating less or go on a keto (low carbohydrate) diet or you're fasting, this may increase your risk of diabetic ketoacidosis. Talk to your healthcare team before making any big changes.
Prepare before an operation or a procedure
If you're going to have an operation or a procedure where you will need to stop eating for 12 hours or more (eg, a colonoscopy or dental surgery), ask your healthcare team when you should stop and restart your Jardiamet. You may need to stop your Jardiamet 3 days before the operation or procedure.
Fasting during Ramadan
If you are fasting during Ramadan and you're still getting enough carbohydrates, you can keep taking Jardiamet. It's important to talk to your healthcare provider about getting enough carbohydrates and drinking plenty of water while taking Jardiamet. It’s not recommended to start Jardiamet as a new medicine immediately before or during Ramadan.
Are you pregnant, trying for a baby or breastfeeding?
It's important to talk to your healthcare provider as soon as possible if you're trying to get pregnant, are pregnant or breastfeeding. You may need to change to another diabetes medicine.
Tell your healthcare team if you are taking any other medicines
Jardiamet may interact some medicines and herbal supplements, so check with your doctor or pharmacist before starting Jardiamet and before starting any new medicines.
Exercising and diet
It's important to keep up your healthy diet and exercise while you're taking Jardiamet. Jardiamet works best when used in combination with good nutrition and regular exercise. It's a good idea to cut down on foods with added sugar if you have diabetes. However, ask your healthcare provider for advice before starting a low-calorie, reduced carbohydrate or keto diet. Having too few carbohydrates in your diet while you are taking Jardiamet may increase your risk of ketoacidosis.
Note: You should avoid a low carbohydrate (ketogenic or keto) diet while you're taking Jardiamet as it may increase your risk of ketoacidosis.
Marathon or long distance runners
Being dehydrated and not eating enough carbohydrates can lead to high ketone levels, which can cause a serious but rare side effect called ketoacidosis. If you are going to run a long distance or marathon while you are taking Jardiamet, it's important to let your healthcare provider know. You may need to stop Jardiamet the day before the marathon and restart 24 hours or so afterwards when you are well hydrated and eating normally.
Blood glucose testing with a glucometer
Jardiamet won't cause low blood glucose levels (hypoglycaemia) unless you're also taking insulin and/or sulfonylureas (eg, glipizide or gliclazide tablets). If so, you still need to check your glucose levels with a glucometer regularly to make sure they are safe.
If you're not on insulin or sulfonylureas, you may still choose to check your glucose levels to see the effects of Jardiamet. It's also important to check your HbA1c 3 months after starting Jardiamet.
You may need a blood glucose test and a ketone test if you are unwell with vomiting (being sick) or diarrhoea (runny poo). Ask your healthcare provider for advice. Read more about diabetes blood glucose testing and diabetes sick day plan.
