Cetirizine
Sounds like 'se-tih-rih-zeen'
Key points about cetirizine
- Cetirizine is an antihistamine used to treat and prevent allergies such as hay fever.
- It's also called Zista®, Histaclear®, Zyrtec®, Razene® or Zetop®.
- Find out how to take it safely and possible side effects.

Cetirizine is used to treat and prevent allergies such as hay fever (sneezing, runny or itchy nose, itchy eyes) or skin allergies such as hives (itching, redness, lumps). It works by blocking a chemical in your body, called histamine, that's released during an allergic reaction.
Cetirizine belongs to a group of medicines known as antihistamines. Cetirizine is a non-sedating antihistamine, which means it's less likely to cause drowsiness or make you feel sleepy.
In Aotearoa New Zealand, cetirizine is available as capsules or tablets (10 mg) or as a liquid (1 mg in 1 mL).
You can buy cetirizine over the counter in pharmacies, supermarkets and other shops. You can also get cetirizine with a prescription from a prescriber.
Read more about antihistamines.
- The usual dose of cetirizine for adults, and children 12 years of age or over, is 1 tablet (10 milligrams) once a day.
- The dose for children under 12 years will depend on their age and weight. Your healthcare provider or pharmacist will advise you on the correct dose for your child.
- You can just take cetirizine on the days you need it. It can be restarted if the symptoms come back.
- Some people take cetirizine for a few weeks when their allergies are a problem, such as in spring. Others take it long-term to help control allergy symptoms.
- Timing: Take cetirizine once a day at the same time each day.
- Food: You can take cetirizine with or without food.
- Capsules or tablets: Swallow the tablet whole, with a glass of water.
- Liquid cetirizine: Shake the bottle well and use an oral syringe or measuring spoon to measure each dose.
- Missed dose: It isn't harmful if you miss your cetirizine dose. If you forget to take your dose, and you usually take it regularly, take it as soon as you remember that day. If it's less than 12 hours for your next dose, just take the next dose at the usual time. Don't take double the dose.
- Are you pregnant, trying for a baby or breastfeeding?
- Do you have epilepsy?
- Do you have any problems with the way your kidneys work?
- Are you taking or using any other medicines? This includes any medicines that you can buy without a prescription, as well as herbal and complementary medicines.
If so, it’s important that you tell your healthcare provider or pharmacist before you start cetirizine.
Sometimes a medicine isn’t suitable for a person with certain conditions, or it can only be used with extra care.
Here are some things to know when you're taking cetirizine. Other things may be important as well, so ask your healthcare provider what you should know about.
- Alcohol: Limit drinking alcohol while you’re taking cetirizine. It may increase your chance of side effects such as feeling sleepy.
- Driving: Some people might feel sleepy when taking cetirizine. Be careful when driving or using tools until you know how this medicine affects you.
- Other medicines: Cetirizine may interact with some medicines so check with your pharmacist before starting cetirizine or before starting any new medicines. If you take it with other antihistamines, such as some cough and cold medicines, it may make you even more sleepy.
Like all medicines, cetirizine can cause side effects, although not everyone gets them. Often side effects improve as your body adjusts to the new medicine.
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Read more about medicines and side effects and reporting a reaction you think might be a side effect.
The following links provide further information on cetirizine:
Razene(external link) Medsafe Consumer Medicine Information, NZ
Cetirizine(external link) New Zealand Formulary Patient Information
Brochures
Medicines and side effects(external link) Healthify He Puna Waiora, NZ, 2024
5 questions to ask about your medications(external link) Health Quality and Safety Commission, NZ, 2019 English(external link), te reo Māori(external link)
References
- Cetirizine hydrochloride(external link) New Zealand Formulary
- Antihistamines(external link) New Zealand Formulary
- Razene(external link) Medsafe datasheet, NZ
- Zista(external link) Medsafe datasheet, NZ
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Allergic rhinitis – diagnosis and treatment(external link) Pharmaceutical Journal, UK, 2025
Brochures
Medicines and side effects
Healthify He Puna Waiora, NZ, 2024
Health Quality and Safety Commission, NZ, 2019 English, te reo Māori
Credits: Healthify editorial team. Healthify is brought to you by Health Navigator Charitable Trust.
Reviewed by: Stephanie Yee, Pharmacist, Auckland.
Last reviewed: